Blar i forfatter "Frye, Stephan Alfons"

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    • AMR-Diag: Neural network based genotype-to-phenotype prediction of resistance towards β-lactams in Escherichia coli and Klebsiella pneumoniae 

      Avershina, Ekaterina; Sharma, Priyanka; Taxt, Arne Michael; Singh, Harpreet; Frye, Stephan Alfons; Paul, Kolin; Kapil, Arti; Naseer, Mohammed Umaer; Kaur, Punit; Ahmad, Rafi (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-29)
      Antibiotic resistance poses a major threat to public health. More effective ways of the antibiotic prescription are needed to delay the spread of antibiotic resistance. Employment of sequencing technologies coupled with the use of trained neural network algorithms for genotype-to-phenotype prediction will reduce the time needed for antibiotic susceptibility profile identification from days to ...

    • Rapid identification of pathogens, antibiotic resistance genes and plasmids in blood cultures by nanopore sequencing 

      Taxt, Arne Michael; Avershina, Ekaterina; Frye, Stephan Alfons; Naseer, Mohammed Umaer; Ahmad, Rafi (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-06)
      Bloodstream infections (BSI) and sepsis are major causes of morbidity and mortality worldwide. Blood culture-based diagnostics usually requires 1–2 days for identification of bacterial agent and an additional 2–3 days for phenotypic determination of antibiotic susceptibility pattern. With the escalating burden of antimicrobial resistance (AMR) rapid diagnostics becomes increasingly important to ...